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Moderate squamous dysplasia causing laryngeal leukoplakia

Return to: Laryngeal leukoplakia white plaques on vocal cords

Return to: Overview of squamous dysplasia 

Go to: Severe squamous dysplasia or Carcinoma in situ causing laryngeal leukoplakia 

Moderate squamous dysplasia is characterized by architectural abnormality, disordered maturation, loss of polarity, and mitoses, that extends into the middle third of the mucosa, and is frequently accompanied by a higher degree of cytologic abnormality. The nuclei are generally more pleomorphic and hyperchromatic than that ascribed to mild dysplasia. Most often when one looks at this form of dysplasia the first thought is "this is dysplastic" and then an secondary algorithmic approach is needed to correctly classify the degree of dysplasia. 

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