Iowa Head and Neck Protocols

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KLS Martin, LP

Hemostatix Medical Technologies, LLC

Boston Medical Products Inc.

Lumenis

KeyPentax

Synovis Micro Companies Alliance, Inc

Tom Benda, JR., M.D.

The Potash Family

UIHC Melanoma and Sarcoma Tissue Bank

Karl Storz-Endoskope

Heartland Regional Chapter of SOHN

Jon and Veda Foster

The Department of Otolaryngology and the University of Iowa wish to acknowledge the support of those who share our goal in improving the care of patients we serve. The University of Iowa appreciates that supporting benefactors recognize the University of Iowa's need for autonomy in the development of the content of the Iowa Head and Neck Protocols.

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Pleomorphic Adenoma / Benign Mixed Tumor

 see also: Case Example Deep Lobe Parotid Tumor Parapharyngeal Space

and Pleomorphic Adenoma

  •  Benign, slow-growing, heterogenous tumor made up of epithelial, myoepithelial, and stromal components
  •  Small pleomorphic adenomas can be homogeneously enhancing (<2 cm)
  •  Large tumors are distinctly lobulated and inhomogeneous
  •  Deep tumors (10-20%) are pear-shaped and push into the parapharyngeal space medially
  •  Quite variable in size, can be found as 6-8 cm lesions when located in deep lobe
  •  Calcification may be present, can help to distinguish from Warthin tumor
  •  Contrast-enhanced CT or MR are adequate study modalities
  •  Most common parotid space tumor (80% of all parotid masses)
  •  Most common in ages >40, 1:2 male to female ratio
  •  Recurrent pleomorphic adenomas are usually multifocal due to spillage during surgery
  •  Malignant transformation in 15% if left untreated
     











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