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Pleomorphic Adenoma / Benign Mixed Tumor

 see also: Case Example Deep Lobe Parotid Tumor Parapharyngeal Space

and Pleomorphic Adenoma

  •  Benign, slow-growing, heterogenous tumor made up of epithelial, myoepithelial, and stromal components
  •  Small pleomorphic adenomas can be homogeneously enhancing (<2 cm)
  •  Large tumors are distinctly lobulated and inhomogeneous
  •  Deep tumors (10-20%) are pear-shaped and push into the parapharyngeal space medially
  •  Quite variable in size, can be found as 6-8 cm lesions when located in deep lobe
  •  Calcification may be present, can help to distinguish from Warthin tumor
  •  Contrast-enhanced CT or MR are adequate study modalities
  •  Most common parotid space tumor (80% of all parotid masses)
  •  Most common in ages >40, 1:2 male to female ratio
  •  Recurrent pleomorphic adenomas are usually multifocal due to spillage during surgery
  •  Malignant transformation in 15% if left untreated

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