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Jon and Veda Foster


Synovis Micro Companies Alliance, Inc

Tom Benda, JR., M.D.

The Potash Family

UIHC Melanoma and Sarcoma Tissue Bank

Karl Storz-Endoskope

Heartland Regional Chapter of SOHN

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Squamous Cell Carcinoma - Tonsil

  •  Epithelial tumors of epidermoid lineage arising in the oropharynx mucosa
  •  Most commonly noted as an enhacing mass with deep invasive margins
  •  Size at discovery is highly variable, from clinically inapparent to enormous exophytic mass
  •  CT findings: small masses may be indistinguishable from asymmetric tonsil, large lesions enhance with contrast, invade surrounding tissue and commonly show spread to level 2a internal jugular chain
  •  MR findings: isointense to muscle on T1, iso- to slightly hyperintense on T2, tumor enhancement on T1 post-contrast (fat-saturation highly recommended) 
  •  Make certain to assess for perineural spread (especially CN V3)
  •  HPV infection, ethanol, and smoking are all risk factors for disease development
  •  Cervical lymphadenopathy is seen in 60% of presentations
  •  Most common in men over the age of 40
  •  Recurrence is most common cause of death and usually occurs within 24 months
  •  Metastasis occurs to lungs > bones > liver

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