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titlePotential Consequences of DNA Test Results

Surprising findings about family relationships

  • New relatives discovered by genetic matching
  • Discovery of genetic relationship between your parents
  • Different relationship than expected with other tested family members

Surprising prediction of ancestry composition

  • Individuals contain a genetic mixture representative of their ancestry through human history

Surprising discovery of genetic susceptibility to disease

  • You and/or your children may have an increased chance of developing an incurable genetic disease
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titleHypothetical Concerns Over DNA Testing

Direct-to-consumer DNA testing is relatively new, thus it is unclear at this time what some of the consequences may be in the future. Consider this, you may discover a 1st cousin that is a child of an aunt/uncle that was placed for adoption as a child 40 years ago. This child would have been born in 1975, the year Fred Sanger published an article describing a technique for sequencing DNA. The Sanger sequencing method, and its modifications, fueled the genome era. Nobody - not even Fred Sanger - could have envisioned in 1975 how easy it is today to discover genetic relationships through broadly commercialized genetic testing. I expect there are things that will be discovered in the future due to the availability of genetic testing, but these future discoveries are not currently obvious. Recognize, however, that you control your test results. They can be deleted by you at any time.

Areas of Potential Concern in the Future

  • Maternity and Paternity - as more people are tested, it will become increasingly easy to reveal personal identity through genetic relationships
  • Forensics - DNA forensics currently uses a different set of genetic markers than what is used by 23andMe and similar companies; however, the availability of large databases of genetically characterized individuals is apparently attracting the attention of law enforcement
  • Discrimination - genetic data related to health information could be used by employers or health insurance companies; however, laws exist that forbid these practices (e.g., Genetic Information Nondiscrimination Act)
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titleScenarios for Class Discussion
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titleLinks

Are You My Cousin by AJ Jacobs

Is genetic genealogy, the next Facebook of science? by Miguel Vilar

Magazine Editor Sets Out To Join The Global Family Tree on NPR

Joining the Global Family Reunion

With genetic testing, I gave my parents the gift of divorce by George Doe

Genetic testing brings families together by Julia Belluz

DNA Testing on Talk of Iowa

Participation in DNA Relatives blog post to students in September 2014

My Medical Choice by Angelina Jolie

Diary of a Surgery by Angelina Jolie Pitt

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