Despite being described as creatures of the Devil, the vampires in Dracula carry an affinity with Christian symbols, mainly Catholic ones.
You tell me why, when other spiders die small and soon, that one great spider lived for centuries in the tower of the old Spanish church and grew and grew, till, on descending, he could drink the oil of all the church lamps? (168-169)
Renfield's questions parallel aspects of Dracula's livelihood. Both the nobelman and the spider live within ancient ruins (his castle and estate having destroyed churches on the grounds) where they sleep and feed upon the Christians (the churches' "lights") who live in the vicinity. The reference to a Spanish church is a partial connection to the Catholic church, as are many of the tools used against the vampires. Renfield alone reveals the dark relationship between vampires and religion, as he worships Dracula as a god in return for the dominion over small animals. Whereas a follower of Christ is expected to be as pious and loving as he was, Renfield is just as bloodthirsty as Dracula, feeding upon the animals he gathers in order to absorb their life.
The Three Sisters are introduced as perversions of the respectable Christian woman, described by Harker as having "a deliberate voluptuousness which was both thrilling and repulsive" to the point where he regrets his desire for them but does not deny it (32). In comparison to Mina, the Sisters exemplify what would be a pathological sexuality by Victorian standards. At the same time, Mina herself experiences both a sacrilegious ritual and a gender reversal when she is forced by the Count to drink her blood. It reflects the Catholic tradition of communion, in which participants believe they are drinking Christ’s blood in order to achieve salvation; but in this case, Mina is entering into a dark pact that will ultimately result in her damnation. Alongside this ritual is twisting of the birth story of Christ wherein the Holy Virgin Mary nursed him at her breast in order to give him life. In Mina's case, the roles are reverse: Dracula is an unholy figure nursing her into his coven of vampires, trading life for death.
However, while vampires have a connection to Christian symbols, they are extremely susceptible to Catholic idols. Early in the novel the crucifix is introduced as a ward to protect Jonathan during his stay in Dracula's castle, warding him from his captor. Van Helsing quickly equips each of the men in the group with one during their hunt for the vampires and even invokes a holy wafer chip to combat the Three Sisters.